Objective: This study aimed to examine the career resiliency of teachers of special schools based on coping styles with the mediating role of religious beliefs. Method: The statistical population of this descriptive-correlational study consisted of all teachers of special schools in Mazandaran Province, Iran. Through cluster sampling, 200 teachers of special schools were selected. In this study, the Special Education Career Resilience Scale (Sotomayor, 2012), the Coping Inventory for Stressful Situations (Endler & Parker, 1990), and the Centrality of Religiosity Scale-15 (Huber & Huber, 2012) were used. Results: Results showed that problem-focused coping style and emotion-focused coping style affect teachers’ career resiliency positively and negatively, respectively, and there is a significant positive correlation between religious belief and resiliency. In addition, all dimensions of religiosity have a significant positive correlation with coping style (problem-oriented). Moreover, religious beliefs have a mediating role between coping style and resiliency. Conclusion: By teaching appropriate coping styles to teachers, it is possible to increase their career resiliency which enhances the quality of teaching, thereby increasing learners’ ability to learn better.