Objective: This study examined the impact of Picture Exchange Communication System (PECS) training on communication problems in children with autism. Method: Utilizing a multiple-baseline design, three children with autism (two boys ageing 9.6 and 8.9, and one girl ageing 8) were recruited through an intact method. The participants were trained for four 15-20 minute sessions per week.  The sessions were captured, and scored. Results: The findings revealed. One of the participants could master on fourth stage and the other two participants mastered on first stage. Three of them could achieve on generalization. No vocabulary increase was significantly observed. Conclusion: Accordingly, this study concludes that PECS may be used in order to enhance communication problems in children with autism.