Objective: In the present research, in order to pathologically assess the reading skill of Persian students with Vision Impairment, various reading errors and reading  speed  of Persian Braille were analyzed. Method: Based on practical experience of Persian Braille and empirical observation of various reading errors of Persian blind students ,the  normalized test of “National Braille Reading skill” was localized. After gaining the validity and reliability, the test was conducted on a sample of 20 Mashhad students with Vision Impairment, having the age range of 18-28 years with sex segregation, all of whom were chosen based on stratified sampling. Results: On the whole, the percentage of reading errors , from high to low, includes “punctuation errors”, “orthographic  errors”, and “letter and point errors”, respectively. The average score for reading was 55 which was lower than minimum score. Average reading speed was  70 words per minute. There was no significant difference between male and female  students in terms of Braille reading scores and reading speed. Braille reading speed in two-handed  female  students  was more than male ones but  it was not significant. Gender effect on reading scores was also meaningful and it was approved that reading Braille with two hands was accompanied by an increase in the scores. Conclusion: The most prevalent reading error in the sample was “punctuation error”.